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Merck

444200

MDL-12,330A hydrochloride

Cell-permeable and irreversible inhibitor of adenylate cyclase (IC50 = 250 µM).

Synonym(s):

MDL-12,330A, Hydrochloride, cis-N-(2-Phenylcyclopentyl)azacyclotridec-1-en-2-amine, HCl, RMI 12330

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About This Item

Empirical Formula (Hill Notation):
C23H36N2 · xHCl
CAS Number:
40297-09-4
Molecular Weight:
340.55 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00210204
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze
protect from light

Key Documents

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Product Name

MDL-12,330A, Hydrochloride, Cell-permeable and irreversible inhibitor of adenylate cyclase (IC50 = 250 µM).

InChI

1S/C23H36N2.ClH/c1-2-4-6-11-18-23(24-19-12-7-5-3-1)25-22-17-13-16-21(22)20-14-9-8-10-15-20;/h8-10,14-15,21-22H,1-7,11-13,16-19H2,(H,24,25);1H/t21-,22-;/m0./s1

InChI key

CKOPQUCSDBVAQG-VROPFNGYSA-N

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white

solubility

DMSO: 10 mg/mL
water: 3 mg/mL
ethanol: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Related Categories

Biochem/physiol Actions

Cell permeable: yes
Primary Target
Adenylate cyclase
Product does not compete with ATP.
Reversible: no
Target IC50: 250 µM against adenylate cyclase

Disclaimer

Toxicity: Standard Handling (A)

General description

Cell-permeable and irreversible inhibitor of adenylate cyclase (IC50 = 250 µM).
Cell-permeable irreversible inhibitor of adenylate cyclase (IC50 = 250 µM).

Other Notes

Correia-de-Sa, P., and Ribeiro, J.A. 1994. Eur. J. Pharmacol. 271, 349.
Gorczynska, E., et al. 1994. Endocrinology134, 293.
Delpiano, M.A., and Acker, H. 1991. J. Neurochem.57, 291.
Lippe, C., and Ardizzone, C. 1991. Comp. Biochem. Physiol.99, 209.
Guellaen, G., et al. 1977. Biochim. Biophys. Acta 484, 465.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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