444228
MMP-7 Substrate, Fluorogenic
Excellent fluorogenic substrate for MMP-7 (kcat/Km = 1.9 x 10⁵ M⁻¹ s⁻¹).
Synonym(s):
MMP-7 Substrate, Fluorogenic, Matrilysin Substrate, PUMP-1 Substrate, DNP-RPLALWRS
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About This Item
Empirical Formula (Hill Notation):
C52H77N17O14
Molecular Weight:
1164.27
UNSPSC Code:
12352200
Assay:
≥90% (HPLC)
Form:
solid
Quality level:
Storage condition:
OK to freeze, desiccated, protect from light
Quality Level
assay
≥90% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated, protect from light
color
yellow
solubility
10% acetic acid: 1 mg/mL
fluorescence
λex ~280 nm, λem ~360 nm
shipped in
ambient
storage temp.
−20°C
General description
Excellent fluorogenic substrate for MMP-7 (kcat/Km = 1.9 x 105 M-1s-1). Excitation maximum: ~280 nm; emission maximum: ~360 nm. The cleavage occurs at the Ala-Leu bond.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Fluorogenic substrate for MMP-7
Fluorogenic substrate for MMP-7
Product does not compete with ATP.
Reversible: no
kcat/Km = 1.9 x 105 M⁻¹ s⁻¹for MMP-7
Other Notes
DNP-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-OH
Welch, A.R., et al. 1996. Biochemistry35, 10103.
Welch, A.R., et al. 1995. Arch. Biochem. Biophys.324, 59.
Welch, A.R., et al. 1995. Arch. Biochem. Biophys.324, 59.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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