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444228

Sigma-Aldrich

MMP-7 Substrate, Fluorogenic

Excellent fluorogenic substrate for MMP-7 (kcat/Km = 1.9 x 10⁵ M⁻¹ s⁻¹).

Synonym(s):

MMP-7 Substrate, Fluorogenic, Matrilysin Substrate, PUMP-1 Substrate, DNP-RPLALWRS

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About This Item

Empirical Formula (Hill Notation):
C52H77N17O14
Molecular Weight:
1164.27
UNSPSC Code:
12352200

Quality Level

100

Assay

≥90% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

color

yellow

solubility

10% acetic acid: 1 mg/mL

fluorescence

λex ~280 nm
λem ~360 nm

shipped in

ambient

storage temp.

−20°C

General description

Excellent fluorogenic substrate for MMP-7 (kcat/Km = 1.9 x 105 M-1s-1). Excitation maximum: ~280 nm; emission maximum: ~360 nm. The cleavage occurs at the Ala-Leu bond.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Fluorogenic substrate for MMP-7
Product does not compete with ATP.
Reversible: no
kcat/Km = 1.9 x 105 M⁻¹ s⁻¹for MMP-7

Other Notes

DNP-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-OH
Welch, A.R., et al. 1996. Biochemistry35, 10103.
Welch, A.R., et al. 1995. Arch. Biochem. Biophys.324, 59.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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