Key Documents
444255
MMP Inhibitor Set I
The MMP Inhibitor Set I controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Synonym(s):
MMP Inhibitor Set I
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About This Item
Quality Level
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated
protect from light
shipped in
ambient
storage temp.
−20°C
General description
Contains 5 mg each of MMP-2/MMP-9 Inhibitor I (Cat. No. 444241) and MMP-3 Inhibitor II (Cat. No. 444225), and 1 mg each of GM 6001 (Cat. No. 364205), GM 6001, Negative Control (Cat. No. 364210), and MMP-8 Inhibitor I (Cat. No. 444237).
Matrix metalloproteinases (MMP) are a family of zinc-dependent enzymes that include interstitial collagenases, stromelysins, gelatinases, and membrane-type metalloproteinases. They are part of the intricate extracellular matrix (ECM) and are involved in maintaining the integrity of the ECM by removing undesired proteins. MMPs play a key role in the normal physiology of connective tissue during development, morphogenesis, and wound healing. However, the unregulated activity of MMPs has been implicated in a number of disease processes, including arthritis, tumor cell metastasis, and atherosclerosis. As a result of their involvement in various disease states, MMPs have become a target for the development of potential therapeutic inhibitors.
The Calbiochem brand has assembled a convenient set containing 4 inhibitors (and one negative control) with different specificities for the study of the biological activity of MMPs and the physiological mechanisms of MMP activation and inhibition.
The Calbiochem brand has assembled a convenient set containing 4 inhibitors (and one negative control) with different specificities for the study of the biological activity of MMPs and the physiological mechanisms of MMP activation and inhibition.
Biochem/physiol Actions
Primary Target
MMP
MMP
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class Code
10-13 - German Storage Class 10 to 13
Certificates of Analysis (COA)
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