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Merck

48-669MAG

MILLIPLEX® Early Apoptosis Signaling Panel

Premixed Early Apoptosis7-plex Cell Signaling Panel

Synonym(s):

Cell Signaling Magnetic Beads, Cell Signaling Multiplex Kit, Total/Phospho Erk Kit, apoptotic biomarker multiplex, caspase pathway detection, early-stage apoptosis panel, human apoptosis detection kit, programmed cell death assay

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About This Item

NACRES:
NA.47
UNSPSC Code:
12161503

Key Documents

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Product Name

MILLIPLEX® Early Apoptosis Signaling Panel, Premixed Early Apoptosis7-plex Cell Signaling Panel

Quality Level

200

species reactivity

human

manufacturer/tradename

Milliplex®

packaging

1 ea of

technique(s)

multiplexing: suitable

input

cell lysate

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

Biochem/physiol Actions

Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Preparation Note

Recommended storage for kit components is 2 - 8°C.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

  • Measures 7 early-stage apoptosis biomarkers in a single assay
  • Complements late apoptosis panels for full apoptotic pathway coverage
  • Ideal for studying intrinsic and extrinsic apoptotic mechanisms
  • High sensitivity and reproducibility
  • Suitable for limited sample volumes and high-throughput analysis

General description

This panel focuses on biomarkers indicative of early-stage apoptosis. It includes proteins such as cleaved PARP, caspase-9, and other initiators of programmed cell death. These analytes are essential for studying the initiation of apoptosis through intrinsic and extrinsic pathways. The panel is ideal for applications in cancer research, neurodegeneration, and evaluating cytotoxic effects of therapeutic compounds.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 7 analytes in cell lysate samples.

Analytes Included: Bcl-2 (Phospho-Ser70), Bad (Phospho-Ser112), Bax, Caspase-3 (Cleaved Asp175), Caspase-7 (Cleaved Asp198), PARP (Cleaved Asp214), Cytochrome c

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).

signalword

Danger

Storage Class

10 - Combustible liquids

wgk

WGK 3

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2

Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
48-669MAG04053252820724

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