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Merck

487952

NOC-7

A nitric oxide (NO) donor similar to NOC-5 but with a much shorter half-life of NO release.

Synonym(s):

NOC-7, 3-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-propanamine

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About This Item

Empirical Formula (Hill Notation):
C5H14N4O2
CAS Number:
146724-84-7
Molecular Weight:
162.19
UNSPSC Code:
12352200
Assay:
≥90% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light

Key Documents

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InChI key

AXAGAUVQMYPYHM-UHFFFAOYSA-N

InChI

1S/C5H14N4O2/c1-6-4-3-5-8(2)9(11)7-10/h6,11H,3-5H2,1-2H3

assay

≥90% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

color

white

solubility

0.1 M NaOH: soluble, water: soluble

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Biochem/physiol Actions

Cell permeable: no
Primary Target
A nitric oxide (NO) donor
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Irritant (B)

General description

A nitric oxide (NO) donor similar to NOC-5 (Cat. No. 487950) but with a much shorter half-life of NO release. Half-life (t½) in PBS, pH 7.4 is 10 minutes at 22°C. Useful as a short-acting nitrovasodilator. Relatively stable in alkaline solution (pH ≥10.0).

Other Notes

Zhang, P., et al. 1996. Circulation94, 2235.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.

Preparation Note

Following reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O jut prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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