487952
NOC-7
A nitric oxide (NO) donor similar to NOC-5 but with a much shorter half-life of NO release.
Synonym(s):
NOC-7, 3-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-propanamine
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About This Item
Empirical Formula (Hill Notation):
C5H14N4O2
CAS Number:
Molecular Weight:
162.19
UNSPSC Code:
12352200
Assay:
≥90% (HPLC)
Form:
solid
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light
Quality Segment
assay
≥90% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic), protect from light
color
white
solubility
0.1 M NaOH: soluble, water: soluble
shipped in
ambient
storage temp.
−20°C
InChI
1S/C5H14N4O2/c1-6-4-3-5-8(2)9(11)7-10/h6,11H,3-5H2,1-2H3
InChI key
AXAGAUVQMYPYHM-UHFFFAOYSA-N
General description
A nitric oxide (NO) donor similar to NOC-5 (Cat. No. 487950) but with a much shorter half-life of NO release. Half-life (t½) in PBS, pH 7.4 is 10 minutes at 22°C. Useful as a short-acting nitrovasodilator. Relatively stable in alkaline solution (pH ≥10.0).
Biochem/physiol Actions
Cell permeable: no
Primary Target
A nitric oxide (NO) donor
A nitric oxide (NO) donor
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O jut prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.
Other Notes
Zhang, P., et al. 1996. Circulation94, 2235.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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