Ornithine Decarboxylase Inhibitor, POB - Calbiochem

Name: Ornithine Decarboxylase Inhibitor, POB - Calbiochem
Brand: MM

Synonym(s):

N-(4ʹ-Pyridoxyl)-Ornithine(BOC)-OMe, ODC Inhibitor, POB, Ornithine Decarboxylase Inhibitor, POB - Calbiochem

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About This Item

Linear Formula:

C19H31N3O6

NACRES:

NA.28

UNSPSC Code:

12352200

Form:

(White to off-white solid)

Storage condition:

OK to freeze

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Properties

form

(White to off-white solid)

Quality Segment

100

storage condition

OK to freeze

solubility

soluble (H2O (1 mg/ml))

storage temp.

2-8°C

Description

General description

A cell-permeable pyridoxyl-ornithine compound that acts as an effective analog of the transition state coenzyme-substrate adduct during orthithine decarboxylase- (ODC) catalyzed conversion of L-orthithine to Pultrescine. POB is typically 5- to 10-fold more potent than DFMO (Cat. No. 288500) in inhibiting intracellular ODC activity and tumor cell growth in cultures, while exhibiting little effect against the growth of nontumorigenic human aortic smooth muscle cells.

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