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Merck

5.04344

(+)-WIN 55,212-2 mesylate - CAS 131543-23-2 - Calbiochem

Synonym(s):

(+)-WIN 55,212-2 mesylate - CAS 131543-23-2 - Calbiochem, WIN 55,212-2 MESYLATE, WIN55, R(+)-WIN 55,212-2 ,MESYLATE HIGH AFFINIT Y CANNABI, R(+)-WIN 55,212-2 MESYLATE, WIN 55,212-2, (R)-(+)-(2,3; Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1.2.3-de]-1,4-benzoxazin-6-yl)-1-naphthalenylmethanonemesy;, 212-2Me

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About This Item

Empirical Formula (Hill Notation):
C28H30N2O6S
CAS Number:
Molecular Weight:
522.61
MDL number:
UNSPSC Code:
12352200

Assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

off-white

solubility

DMSO: 30 mg/mL

storage temp.

−20°C

General description

A potent agonist for cannabinoid receptors with higher affinity to subtype 2 (CB2, Ki = 3.3 nM) than to subtype 1 (CB1, Ki = 62.3 nM).

Biochem/physiol Actions

Primary Target
CB receptors
Target Ki: 62.3 and 3.3 nM for CB₁ and CB₂ receptors, respecively.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -30°C.

Other Notes

Palazzo, E., et al. 2012. Neuroscience.85, 327.
Ferraro, L., et al. 2001. Cerebral Cortex.11,728.
Price, T., et al. 2004. Br. J. Pharmacol.142, 257.
Martellotta, M., et al. 1998. Neuroscience.85, 327.

Griffin,G., et al. 1998. J. Pharmacol. Exp. Ther.285, 553.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Certificates of Analysis (COA)

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