5.04463
BINA
동의어(들):
BINA, Biphenyl-indanone A
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C30H30O4
CAS 번호:
Molecular Weight:
454.56
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
OK to freeze, protect from light
assay
≥98% (HPLC)
Quality Segment
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
DMSO: 18 mg/mL
storage temp.
2-8°C
InChI
1S/C30H30O4/c1-18-19(2)28-25(15-26(29(28)31)22-7-3-4-8-22)16-27(18)34-17-20-6-5-9-24(14-20)21-10-12-23(13-11-21)30(32)33/h5-6,9-14,16,22,26H,3-4,7-8,15,17H2,1-2H3,(H,32,33)
InChI key
KMKBEESNZAPKMP-UHFFFAOYSA-N
General description
A selective positive allosteric modulator for mGlu receptor subtype 2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2). No effect on other mGlu receptor subtypes. Exhibits antipsychotic and anxiolytic properties in mice.
Biochem/physiol Actions
Primary Target
mGlu₂
mGlu₂
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Bonnefous, C., et al. 2005. Bioorg. Med. Chem. Lett.15, 4354.
Galici, R., et al. 2006. J. Pharmacol. Exp. Ther.318, 173.
Benneyworth, M., et al. 2007. Mol. Pharmacol.72, 477.
Sheffler, D., et al. 2011. ACS Chem. Neurosci.2, 382.
Galici, R., et al. 2006. J. Pharmacol. Exp. Ther.318, 173.
Benneyworth, M., et al. 2007. Mol. Pharmacol.72, 477.
Sheffler, D., et al. 2011. ACS Chem. Neurosci.2, 382.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.