5.04523
CP-101,606
동의어(들):
CP-101,606, Traxoprodil, CP-101606, (1S,2S)-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol, NMDA Antagonist VI
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C20H25NO3
CAS 번호:
Molecular Weight:
327.42
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
OK to freeze, protect from light
assay
≥98% (HPLC)
Quality Segment
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
DMSO: 35 mg/mL
storage temp.
2-8°C
InChI
1S/C20H25NO3/c1-15(19(23)16-7-9-18(22)10-8-16)21-13-11-20(24,12-14-21)17-5-3-2-4-6-17/h2-10,15,19,22-24H,11-14H2,1H3/t15-,19+/m0/s1
InChI key
QEMSVZNTSXPFJA-HNAYVOBHSA-N
General description
A highly selective antagonist for NR2B subunit containing NMDA receptors (IC50 = 0.039 µM for NR2B and >100 µM for NR2A, NR2C, and NR2D). Widely used as neuroprotective, analgesic, antidepressant, and anti-Parkinsonian agent in research.
Biochem/physiol Actions
Primary Target
NMDA receptors
NMDA receptors
Target IC50: 0.039 µM for NR2B and >100 µM for NR2A, NR2C, and NR2D
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Taniguchi, K., et al. 2009. British J. Pharmacol.122, 809.
Menniti, F., et al. 1997. Eur. J. Pharmacol.331, 117.
Nicholson, K., et al. 2007. Behavioural Pharmacology18, 731.
Bullock, M., et al. 2006. Annals of the New York Academy of Sciences890, 51.
Preskorn, S., et al. 2008. J. Clin. Psychopharmacol.28, 631.
Yurkewicz, L., et al. 2005. J. Neurotrauma.22, 1428.
Menniti, F., et al. 1997. Eur. J. Pharmacol.331, 117.
Nicholson, K., et al. 2007. Behavioural Pharmacology18, 731.
Bullock, M., et al. 2006. Annals of the New York Academy of Sciences890, 51.
Preskorn, S., et al. 2008. J. Clin. Psychopharmacol.28, 631.
Yurkewicz, L., et al. 2005. J. Neurotrauma.22, 1428.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.