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5.04820

Cinnabarinic acid

Name: Cinnabarinic acid
Brand: MM

Synonym(s):

Cinnabarinic acid, 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₈N₂O₆

CAS Number:

606-59-7

Molecular Weight:

300.22

MDL number:

MFCD18379297

UNSPSC Code:

12352106

NACRES:

NA.77

Assay

≥98% (HPLC)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze
protect from light

color

red

solubility

DMSO: 25 mM

storage temp.

−20°C

SMILES string

Nc1[c](cc2[o]c3c(nc2c1C(=O)O)c(ccc3)C(=O)O)=O

InChI

1S/C14H8N2O6/c15-10-6(17)4-8-12(9(10)14(20)21)16-11-5(13(18)19)2-1-3-7(11)22-8/h1-4H,15H2,(H,18,19)(H,20,21)

InChI key

FSBKJYLVDRVPTK-UHFFFAOYSA-N

Related Categories

Bioactive Small Molecule Agonists

General description

A partial, low-potency agonist highly selective for mGlu₄ receptors (EC₅₀ >100 µM, no effect on other mGlu subtype receptors). Used in assessing the functional roles of mGlu₄ receptors in a variety of research areas, such as excitotoxic cell death, apoptosis, neuroinflammation, inflammation, and neuroimmune communication.

Biochem/physiol Actions

Primary Target
mGlu₄ receptors

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Slight warming is required for complete solubilization.

Other Notes

Fazio, Francesco, et al. 2012. Mol. Pharmacol.81, 643.

Volpi, C., et al. 2012. Neuropharmacol.63, 501.
Hiramatsu, R., et al. 2008. J. Cell Biochem.103, 42.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKU	GTIN
5.04820.0001	04055977243550

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