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Merck

5.04820

Cinnabarinic acid

Synonym(s):

Cinnabarinic acid, 2-Amino-3-oxo-3H-phenoxazine-1,9-di­carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C14H8N2O6
CAS Number:
606-59-7
Molecular Weight:
300.22
UNSPSC Code:
12352106
NACRES:
NA.77
MDL number:
MFCD18379297

Key Documents

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SMILES string

Nc1[c](cc2[o]c3c(nc2c1C(=O)O)c(ccc3)C(=O)O)=O

InChI

1S/C14H8N2O6/c15-10-6(17)4-8-12(9(10)14(20)21)16-11-5(13(18)19)2-1-3-7(11)22-8/h1-4H,15H2,(H,18,19)(H,20,21)

InChI key

FSBKJYLVDRVPTK-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

red

solubility

DMSO: 25 mM

storage temp.

−20°C

Quality Level

100

Related Categories

Biochem/physiol Actions

Primary Target
mGlu₄ receptors

Disclaimer

Toxicity: Standard Handling (A)

General description

A partial, low-potency agonist highly selective for mGlu4 receptors (EC50 >100 µM, no effect on other mGlu subtype receptors). Used in assessing the functional roles of mGlu4 receptors in a variety of research areas, such as excitotoxic cell death, apoptosis, neuroinflammation, inflammation, and neuroimmune communication.

Other Notes

Fazio, Francesco, et al. 2012. Mol. Pharmacol.81, 643.

Volpi, C., et al. 2012. Neuropharmacol.63, 501.
Hiramatsu, R., et al. 2008. J. Cell Biochem.103, 42.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Slight warming is required for complete solubilization.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
5.04820.000104055977243550

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