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Merck

5.04859

2-N-Hexadecanoylamino-4-nitrophenylphosphorylcholine

≥98% (TLC), solid, acid sphingomyelinase substrate, Calbiochem®

Synonym(s):

2-N-Hexadecanoylamino-4-nitrophenylphosphorylcholine, HDA-PC

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About This Item

CAS Number:
60438-73-5
MDL number:
MFCD00051274
UNSPSC Code:
12352200
NACRES:
NA.77

Key Documents

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Product Name

2-N-Hexadecanoylamino-4-nitrophenylphosphorylcholine,

SMILES string

[P](=O)([O-])(OCC[N+](C)(C)C)Oc1c(cc(cc1)[N+](=O)[O-])NC(=O)CCCCCCCCCCCCCCC.O

InChI

1S/C27H48N3O7P.H2O/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-27(31)28-25-23-24(29(32)33)19-20-26(25)37-38(34,35)36-22-21-30(2,3)4;/h19-20,23H,5-18,21-22H2,1-4H3,(H-,28,31,34,35);1H2

InChI key

CDTKXKMMWVIQDN-UHFFFAOYSA-N

assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

off-white

solubility

methanol: 25 mg/mL

storage temp.

−20°C

Quality Level

100

Related Categories

General description

2-N-Hexadecanoylamino-4-nitrophenylphosphorylcholineis a synthetic chromogenic analog of sphingomyelin.

Other Notes

Levade, T., et al. 1983. J. Neurochem.40, 1762.
Gal, A.E., and Fash, F.J. 1976. Chem. Phys. Lipids16, 71.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Slight warming is required for complete solubilization.

Application

2-N-Hexadecanoylamino-4-nitrophenylphosphorylcholinemaybe used to evaluate sphingomyelinase activity. It is also suitable forselective assay of brain sphingomyelinase without intrusion from neutralsphingomyelinase.

Disclaimer

Toxicity: Standard Handling (A)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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