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Merck

5.04913

Aniracetam

Synonym(s):

Aniracetam, 1-(4-methoxybenzoyl)pyrrolidin-2-one, Draganon, Sarpul, Ampamet, Memodrin, Referan, Memodrin, Referan, 1-(4-methoxybenzoyl)pyrrolidin-2-one, Draganon, Sarpul, Ampamet

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About This Item

Empirical Formula (Hill Notation):
C12H13NO3
CAS Number:
72432-10-1
Molecular Weight:
219.24
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00153767
Assay:
≥99% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze, protect from light

Key Documents

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form

solid

manufacturer/tradename

Calbiochem®

SMILES string

N2(CCCC2=O)C(=O)c1ccc(cc1)OC

InChI

1S/C12H13NO3/c1-16-10-6-4-9(5-7-10)12(15)13-8-2-3-11(13)14/h4-7H,2-3,8H2,1H3

InChI key

ZXNRTKGTQJPIJK-UHFFFAOYSA-N

assay

≥99% (HPLC)

storage condition

OK to freeze, protect from light

color

white

solubility

DMSO: 100 mM

storage temp.

2-8°C

Quality Level

100

Related Categories

General description

A positive allosteric modulator selective for AMPA receptors. Slows down AMPA receptor deactivation rate without altering the agonist potency. A leading candidate of ampakine nootropic for cognitive enhancement. Widely used in studies in a variety of brain functions (i.e. learn and memory, cognition) and disorders (depression, anxiety disorder, Alzheimer′s disease, and aging).

Please note that the molecular weight for this compound is batch-specific due to variable water content.

Biochem/physiol Actions

Primary Target
AMPA receptors

Other Notes

Koliaki, C., et al. 2012. CNS Neuroscience & Therapeutics.18, 302.
Lynch, G., et al. 2011. Pharmacol. Biochem. Behav.99, 116.
Nakamura, K., et al. 2001. Eur. J. Pharmacol.420, 33.
Ito, I. et al., 1990. J. Physiol.424, 553.
Isaacson et al., 1991. PNAS.88, 1093.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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