Skip to Content
Merck

5.05016

CX546

Synonym(s):

CX546, AMPA Positive Allosteric Modulator, CX546, CX-546, CX 546

Sign In to View Organizational & Contract Pricing.

Select a Size

All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C14H17NO3
CAS Number:
215923-54-9
Molecular Weight:
247.29
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD01860868

SMILES string

N3(CCCCC3)C(=O)c1cc2c(cc1)OCCO2

InChI

1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2

InChI key

LJUNPHMOGNFFOS-UHFFFAOYSA-N

assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

off-white

solubility

DMSO: soluble

storage temp.

2-8°C

Quality Level

100

Biochem/physiol Actions

Primary Target
AMPA

Disclaimer

Toxicity: Standard Handling (A)

General description

A positive allosteric modulator selective for the AMPA receptors. Used in studies related to Schizophrenia, neuroplasticity, Autism and neuronal differentiation.

Other Notes

Silverman, L., et al. 2013. Neuropharmacol.64, 268.
Peleg-Raibstein, D., et al. 2012. Curr. Antipsych.2012, 361.

Schitine, C., et al. 2012. Eur. J. Neurosci.35, 1672.
Lipina, T., et al. 2006. Neuropsychopharmacology.32, 745.
Arai, C., et al. 2004. Neurosci.123, 1011.
Nagarajan, N., et al. 2001. Neuropharmacol.41, 650.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service