5.05051
2,3 cis-Piperidine dicarboxylic acid
Synonym(s):
2,3 cis-Piperidine dicarboxylic acid, Ionotropic Glutamate Receptor Antagonist, PDA, cis PDA, cis-Piperidine-2,3-dicarboxylic acid
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About This Item
Empirical Formula (Hill Notation):
C7H11NO4
CAS Number:
Molecular Weight:
173.17
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
Storage condition:
OK to freeze, protect from light
assay
≥98% (HPLC)
Quality Level
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
water: 100 mM
storage temp.
2-8°C
SMILES string
N1C(C(CCC1)C(=O)O)C(=O)O
InChI
1S/C7H11NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h4-5,8H,1-3H2,(H,9,10)(H,11,12)
InChI key
PTLWNCBCBZZBJI-UHFFFAOYSA-N
General description
A non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors. Used in blocking general excitatory synaptic transmissions.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Tong, G., et al. 1994. Neuron13, 1195.
Leach, J., et al. 1986. Eur. J. Pharmacol.121, 173.
Watkins, C., et al. 1981. Annu. Rev. Pharmacol. Toxicol.21, 165.
Leach, J., et al. 1986. Eur. J. Pharmacol.121, 173.
Watkins, C., et al. 1981. Annu. Rev. Pharmacol. Toxicol.21, 165.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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