5.05481
MRS 2211 - Calbiochem
Synonym(s):
MRS 2211 - Calbiochem, 2-[(2-Chloro-5-nitrophenyl)azo]-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde sodium salt, P2Y13 Purinergic Receptor Antagonist, MRS2211, MRS 2211, MRS-2211
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About This Item
Empirical Formula (Hill Notation):
C14H9ClN4Na3O8P
Molecular Weight:
496.64
UNSPSC Code:
12352200
PubChem Substance ID:
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
dark red
solubility
water: 70 mM
storage temp.
−20°C
SMILES string
CC1=C(C(=C(C(=N1)N=NC2=C(C=CC(=C2)[N+](=O)[O-])Cl)COP(=O)([O-])[O-])C=O)O.[Na+].[Na+]
General description
A highly selective and competitive antagonist of P2Y13 purinergic receptor (pIC50 = 5.97). Exhibits about 20-fold greater selectivity over P2Y1 and P2Y12 receptors.
Biochem/physiol Actions
Primary Target
P2Y13
P2Y13
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Kim, Y.C., et al. 2005. Biochem. Pharmacol.70, 266.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_c
Not applicable
Certificates of Analysis (COA)
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