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Merck

5.05873

(R)-Baclofen

Synonym(s):

(R)-Baclofen, STX 209, GABA B Agonist, Baclofen, Arbaclofen, STX 209, GABAB Agonist, Baclofen, Arbaclofen

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About This Item

Empirical Formula (Hill Notation):
C10H12ClNO2
CAS Number:
69308-37-8
Molecular Weight:
213.66
UNSPSC Code:
12352200

Key Documents

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InChI key

KPYSYYIEGFHWSV-UHFFFAOYSA-N

InChI

1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

off-white

solubility

water: soluble

storage temp.

2-8°C

Quality Level

100

Biochem/physiol Actions

Primary Target
GABAB

Disclaimer

Toxicity: Toxic (F)

General description

A selective agonist of GABAB receptors that is shown to activate K+ conductance in hippocampal neurons. Also acts as an antispastic agent and a skeletal muscle relaxant. It is also an experimental drug to treat autism.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Sodickson, D.L., et al., 1996. J. Neurosci.16, 6374.

Ahuja, S. et al., 1985. Analytical Profile of Drug Substances14, 527.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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