5.05873
(R)-Baclofen
Synonym(s):
(R)-Baclofen, STX 209, GABA B Agonist, Baclofen, Arbaclofen, STX 209, GABAB Agonist, Baclofen, Arbaclofen
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About This Item
Empirical Formula (Hill Notation):
C10H12ClNO2
CAS Number:
Molecular Weight:
213.66
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
Storage condition:
OK to freeze, protect from light
assay
≥98% (HPLC)
Quality Level
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
off-white
solubility
water: soluble
storage temp.
2-8°C
InChI
1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
InChI key
KPYSYYIEGFHWSV-UHFFFAOYSA-N
General description
A selective agonist of GABAB receptors that is shown to activate K+ conductance in hippocampal neurons. Also acts as an antispastic agent and a skeletal muscle relaxant. It is also an experimental drug to treat autism.
Biochem/physiol Actions
Primary Target
GABAB
GABAB
Preparation Note
Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Sodickson, D.L., et al., 1996. J. Neurosci.16, 6374.
Ahuja, S. et al., 1985. Analytical Profile of Drug Substances14, 527.
Ahuja, S. et al., 1985. Analytical Profile of Drug Substances14, 527.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Toxic (F)
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Certificates of Analysis (COA)
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