(S)-(-)-Raclopride

Name: (S)-(-)-Raclopride
Brand: MM

Synonym(s):

(S)-(-)-Raclopride, Dopamine Receptor D2 Antagonist, (S)-Raclopride, Raclopride

Select a Size

All Photos(1)

About This Item

Empirical Formula (Hill Notation):

C₁₅H₂₀Cl₂N₂O₃

CAS Number:

84225-95-6

Molecular Weight:

347.24

MDL number:

MFCD02179386

UNSPSC Code:

12352200

NACRES:

NA.77

SMILES string

Clc1c(c(c(c(c1)Cl)O)C(=O)NC[C@@H]2N(CCC2)CC)OC

InChI

1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m1/s1

InChI key

WAOQONBSWFLFPE-SECBINFHSA-N

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze
protect from light

color

off-white

solubility

DMSO: 100 mM
ethanol: 25 mM

storage temp.

2-8°C

Quality Level

100

Biochem/physiol Actions

Reversible: yes

Disclaimer

Toxicity: Standard Handling (A)

General description

D₂-like dopamine receptor antagonist targeting D₂R (pKi =8.0), D₃R (pKi = 7.9), and 5-HT1A R (pKi=5.2). Used to explore D₂ like receptor mediated effects in neuropathic pain, and in antagonism studies of DA receptors during heroin usage and cocaine. D₂ Receptor selectivity in various preps shows IC₅₀ values around 32 nM.

Other Notes

Dang, Y. H. et al. 2010. Neurosci.169, 1872.

Platt, D. M. et al. 2010. J. Pharmacol. Exp. Ther.332, 985.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKU	GTIN
5.05877.0001	04055977263138

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service