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Merck

5.05894

Sigma-Aldrich

CGP 7930

Synonym(s):

CGP 7930, GABA B Receptor Antagonist, CGP7930, CGP 7930, CGP-7930

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About This Item

Empirical Formula (Hill Notation):
C19H32O2
CAS Number:
57717-80-3
Molecular Weight:
292.46
MDL number:
MFCD04040028
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥98% (HPLC)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

pale yellow

solubility

DMSO: 100 mM
ethanol: 100 mM

storage temp.

2-8°C

SMILES string

OCC(Cc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)(C)C

InChI

1S/C19H32O2/c1-17(2,3)14-9-13(11-19(7,8)12-20)10-15(16(14)21)18(4,5)6/h9-10,20-21H,11-12H2,1-8H3

InChI key

XLWJPQQFJNGUPA-UHFFFAOYSA-N

General description

A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABAB receptor. Shown to modulate GABAB receptor in the high affinity state and thereby increases agonist affinity for the receptor. Also enhances agonist potency and efficacy even on recombinant GABAB receptors. Exhibits anxiolytic effects in rodents.

Other Notes

Adams, C. et al., 2007. CNS Drug Rev.13, 308.
Pin, J.P., et al., 2007. Curr. Neuropharmacol.5, 195.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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