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506102

Sigma-Aldrich

p21-Activated Kinase Inhibitor, Negative Control

The p21-Activated Kinase Inhibitor, Negative Control for p21-Activated KInase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Synonym(s):

p21-Activated Kinase Inhibitor, Negative Control, H₂N-RKKRRQRRR~G~PPVIAP APEHTKSVYTRS-CO₂H, PAK18-R192A, PAK Inhibitor I, Negative Control, H₂N-RKKRRQRRR~G~PPVIAPAPEHTKSVYTRS-CO₂H, PAK18-R192A, PAK Inhibitor I, Negative Control

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About This Item

Empirical Formula (Hill Notation):
C143H247N55O37
Molecular Weight:
3328.84
UNSPSC Code:
12352200

Quality Level

100

Assay

≥97% (HPLC)

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)
protect from light

solubility

water: 1 mg/mL
DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

The inhibitory activity of p21-Activated Kinase Inhibitor PAK18 (Cat. No. 506101) is rendered inactive with a single amino acid mutation (R192A). Serves as an inactive control peptide.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Inactive control peptide for p21-Activated Kinase Inhibitor PAK18
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Physical form

Supplied as trifluoroacetate salt

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

H-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg~Gly~Pro-Pro-Val-Ile-Ala-Pro-Ala-Pro-Glu-His-Thr-Lys-Ser-Val-Tyr-Thr-Arg-Ser-OH
Zhao, L., et al. 2006. Nat. Neurosci.9, 234.
Maruta, H., et al. 2002. Methods Mol. Biol.189, 75.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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