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Merck

5.06382

MPTP Hydrochloride

≥98% (TLC), solid, dopaminergic neurotoxin, Calbiochem

Synonym(s):

MPTP Hydrochloride, Dopaminergic neurotoxin, MPTP

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About This Item

Empirical Formula (Hill Notation):
C12H15N · xHCl
CAS Number:
23007-85-4
Molecular Weight:
173.25 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00012790
Assay:
≥98% (TLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze, protect from light

Key Documents

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Product Name

MPTP Hydrochloride,

SMILES string

[Cl-].[N+H]1(CCC(=CC1)c2ccccc2)C

InChI

1S/C12H15N.ClH/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11;/h2-7H,8-10H2,1H3;1H

InChI key

KOWJANGMTAZWDT-UHFFFAOYSA-N

assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

Quality Level

100

drug control

kontrollierte Droge in Deutschland

storage condition

OK to freeze, protect from light

color

white

solubility

water: 100 mg/mL

storage temp.

2-8°C

Related Categories

General description

A neurotoxin that is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism. Widely used in research to induce Parkinson′s disease models in primates.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Langston, J. W., et al. 1985. Trends in Neurosci.8, 79.

Gabriel, T. L., et al. 1999. Nature Med.5, 1403.
Zhang, X., et al. 2010. J. Proteome Res.9, 1496.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

Disclaimer

Toxicity: Toxic (F)

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - STOT SE 1

target_organs

Nervous system

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
5.06382.000104055977243277

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