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Merck

5.08155

Sigma-Aldrich

LP-44 Hydrochloride

Synonym(s):

LP-44 Hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C27H38ClN3OS
CAS Number:
824958-12-5
Molecular Weight:
488.13
MDL number:
MFCD09971090
UNSPSC Code:
12352200

Assay

98% (HPLC)

Quality Level

100

form

solid

potency

0.22 nM Ki

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white

solubility

DMSO: 100 mM
ethanol: 100 mM

storage temp.

2-8°C

InChI

1S/C27H37N3OS.ClH/c1-32-26-15-7-6-14-25(26)30-20-18-29(19-21-30)17-8-2-3-16-27(31)28-24-13-9-11-22-10-4-5-12-23(22)24;/h4-7,10,12,14-15,24H,2-3,8-9,11,13,16-21H2,1H3,(H,28,31);1H

InChI key

DWGKCWWWKHCVDH-UHFFFAOYSA-N

General description

A potent agonist of the 5-HT7 serotonin receptor (Ki= 0.22 nM) with good selectivity against other 5-HT receptors (5-HT1A Ki = 52.7 nM, 5-HT1B Ki = 60 nM). Often used in conjuction with the selective 5-HT7 receptor antagonist, SB-269970 (Cat. No. 506415)

Other Notes

Monti, J. M. et al. 2008. Behar. Brain Res.191, 184.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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