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5.08314

KN-92

Name: KN-92
Brand: MM

InSolution, ≥95%, 5 mM in DMSO, Useful as a negative control for KN-93

Synonym(s):

InSolution KN-92, 2-(N-(4-Methoxybenzenesulfonyl))amino-N-(4-chlorocinnamyl)-N-methylbenzylamine, Phosphate, ( E)-N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-4-methoxybenzenesulfonamide, Phosphate, 2-(N-(4-Methoxybenzenesulfonyl))amino-N-(4-chlorocinnamyl)-N-methylbenzylamine, Phosphate, (E)-N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-4-methoxybenzenesulfonamide, Phosphate

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About This Item

Empirical Formula (Hill Notation):

C₂₄H₂₅ClN₂O₃S · xH₃PO₄

CAS Number:

1135280-28-2

Molecular Weight:

456.98

MDL number:

MFCD24369012

UNSPSC Code:

12352200

NACRES:

NA.77

Assay:

≥95% (HPLC)

Form:

liquid

Storage condition:

OK to freeze, avoid repeated freeze/thaw cycles, desiccated (hygroscopic), protect from light

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Properties

Quality Segment

100

assay

≥95% (HPLC)

form

liquid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles, desiccated (hygroscopic), protect from light

storage temp.

−70°C

SMILES string

[P](=O)(O)(O)O.[S](=O)(=O)(Nc2c(cccc2)CN(C\C=C\c3ccc(cc3)Cl)C)c1ccc(cc1)OC

InChI

1S/C24H25ClN2O3S.H3O4P/c1-27(17-5-6-19-9-11-21(25)12-10-19)18-20-7-3-4-8-24(20)26-31(28,29)23-15-13-22(30-2)14-16-23;1-5(2,3)4/h3-16,26H,17-18H2,1-2H3;(H3,1,2,3,4)/b6-5+;

InChI key

XRQHWVVDNMJDEQ-IPZCTEOASA-N

Description

General description

Useful as a negative control for KN-93 (Cat. No. 422708), a Ca²⁺/CaM kinase II inhibitor.

Biochem/physiol Actions

Reversible: yes

Cell permeable: yes

Packaging

Packaged under inert gas

Physical form

A 5 mM (500 µg/180 µL) sterile-filtered solution of KN-92 (Cat. No. 422709) in DMSO.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 3 months at -20°C.

Other Notes

Fan, G.H., et al. 1999. Mol. Pharmacol.56, 39.
Fan, G.H., et al. 1997. Neuropharmacology36, 1763.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

188.6 °F - (refers to pure substance)

flash_point_c

87 °C - (refers to pure substance)

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