Key Documents

View All Documentation

511075

Platelet Activating Factor-16

Name: Platelet Activating Factor-16
Brand: MM

≥98% (TLC), lyophilized solid, inflammation mediator, Calbiochem^®

Synonym(s):

Platelet Activating Factor-16, PAF (C₁₆), 1-O-Palmityl-2-acetyl- sn-glycero-3-phosphocholine, 1-O-Hexadecyl-2-acetyl- sn-glycero-3-phosphocholine, PAF (C₁₆), 1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine, 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₂₆H₅₄NO₇P

CAS Number:

74389-68-7

Molecular Weight:

523.68

MDL number:

MFCD00043214

UNSPSC Code:

12352211

NACRES:

NA.77

Assay:

≥98% (TLC)

Form:

lyophilized solid

Storage condition:

OK to freeze, desiccated

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Platelet Activating Factor-16, A potent mediator of inflammation that increases vascular permeability. Activates MAP kinases and MAP kinase kinase (MEK) in CHO cells.

Quality Segment

100

assay

≥98% (TLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated

color

white to off-white

solubility

ethanol: 0.5-1 mg/mL, water: soluble

shipped in

ambient

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)C)COCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1

InChI key

HVAUUPRFYPCOCA-AREMUKBSSA-N

Description

General description

Synthetic water-soluble platelet activating factor. A potent mediator of inflammation that increases vascular permeability. Activates MAP kinase and MAP kinase kinase (MEK) in CHO cells.

Synthetic. A potent mediator of inflammation that increases vascular permeability. Activates MAP kinases and MAP kinase kinase (MEK) in CHO cells.

Biochem/physiol Actions

Cell permeable: no

Primary Target
MAP kinases and MAP kinase kinase (MEK)

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C or -70°C) under an inert gas. Aqueous stock solutions are stable for up to 3 days at -20°C. Ethanol stock solutions are stable for up to 3 months at -70°C.

Other Notes

Honda, Z., et al. 1994. J. Biol. Chem. 269, 2307.
Mori, M., et al. 1994. Ann. N.Y. Acad. Sci.744, 107.
Pinckard, R.N., et al. 1992. J. Immunol.148, 3528.
Salari, H., et al. 1992. Biochem. Cell Biol.70, 129.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c