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About This Item
Empirical Formula (Hill Notation):
C35H48N8O11S
CAS Number:
Molecular Weight:
788.87
UNSPSC Code:
12352200
MDL number:
Quality Segment
assay
≥95% (HPLC)
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
ethanol: 10 mg/mL, methanol: 10 mg/mL
shipped in
ambient
storage temp.
2-8°C
InChI
1S/C35H48N8O11S/c1-15-27(47)38-22-10-20-19-7-5-6-8-21(19)41-33(20)55-13-24(34(53)43-12-18(46)9-25(43)31(51)37-15)40-32(52)26(17(3)45)42-28(48)16(2)36-30(50)23(39-29(22)49)11-35(4,54)14-44/h5-8,15-18,22-26,41,44-46,54H,9-14H2,1-4H3,(H,36,50)(H,37,51)(H,38,47)(H,39,49)(H,40,52)(H,42,48)/t15-,16-,17-,18-,22-,23-,24-,25-,26+,35+/m0/s1
InChI key
KPKZJLCSROULON-QKGLWVMZSA-N
General description
Toxic bicyclic heptapeptide isolated from fungi. Useful as a potent and specific F-actin binding agent and inhibitor of F- to G-actin conversion.
Biochem/physiol Actions
Cell permeable: no
Primary Target
F-actin binding agent
F-actin binding agent
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
Other Notes
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Mathews, J.B., et al. 1997. Am. J. Physiol. 272, C254.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Highly Toxic (H)
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
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