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Merck

520224

PPACK, Dihydrochloride, Biotinylated

Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.

Synonym(s):

PPACK, Dihydrochloride, Biotinylated, Biotin-X-D-Phe-Pro-Arg-chloromethylketone, 2HCl

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About This Item

Empirical Formula (Hill Notation):
C43H70ClN10O7S · 2HCl
Molecular Weight:
979.52
UNSPSC Code:
12352200
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Product Name

PPACK, Dihydrochloride, Biotinylated, Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.

assay

≥80% (HPLC and TLC)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

Cell permeable: no
Product does not compete with ATP.
Reversible: no
Target IC50: 110 nM against thrombin

Disclaimer

Toxicity: Standard Handling (A)

General description

Biotin-X-analog of Cat. No. 520222. Specific probe for active serine proteases. Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.
Biotin-X-analog of Cat. No. 520222. Specific probe for active serine proteases. Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.

Other Notes

Williams, E.B., et al. 1989. J. Biol. Chem.264, 7536.

Physical form

In 10 mM HCl.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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