Skip to Content
Merck

Key Documents

View All Documentation

5.31038

Sigma-Aldrich

TAT-Beclin-1, Scrambled

≥95% (HPLC), powder, Beclin-1 activator, Calbiochem®

Synonym(s):

Beclin-1 Activator I, TAT-Beclin-1, Scrambled, H₂N-YGRKKRRQRRR-GG-VGNDFFINHETTGFATEW-CO₂H

Sign Into View Organizational & Contract Pricing

Select a Size

All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C164H251N57O45
Molecular Weight:
3741.10
UNSPSC Code:
12352200
NACRES:
NA.77

Product Name

Beclin-1 Activator I, TAT-Beclin-1, Scrambled,

Assay

≥95% (HPLC)

Quality Level

100

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)
protect from light

color

white

solubility

water: 25 mg/mL

storage temp.

2-8°C

General description

Beclin-1 (267-284), a randomly shuffled peptideis made cell-permeable by attaching covalently to a human immunodeficiency virus(HIV)-1 Tat protein transduction domain via a diglycine linker. Beclin-1activating peptide I, TAT-Beclin-1, is observed to promote autophagy invitro and in vivo in pharmacological research.

Biochem/physiol Actions

Cell permeable: yes
Reversible: yes

Packaging

Packaged under inert gas

Other Notes

H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg~Gly-Gly~Val-Gly-Asn-Asp-Phe-Phe-Ile-Asn-His-Glu-Thr-Thr-Gly-Phe-Ala-Thr-Glu-Trp-OH
Liu, Y., et al. 2013. Proc. Natl. Acad. Sci. USA110, 20364.
Shoji-Kawata, S., et al. 2013. Nature.494, 201.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Beclin-1-Dependent Autophagy Improves Outcomes of Pneumonia-Induced Sepsis
Azadeh N, et al.
Frontiers in Cellular and Infection Microbiology (2021)

Global Trade Item Number

SKUGTIN
5.31038.000104055977242508

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service