5.31038
TAT-Beclin-1, Scrambled
≥95% (HPLC), powder, Beclin-1 activator, Calbiochem®
Synonym(s):
Beclin-1 Activator I, TAT-Beclin-1, Scrambled, H₂N-YGRKKRRQRRR-GG-VGNDFFINHETTGFATEW-CO2H
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About This Item
Empirical Formula (Hill Notation):
C164H251N57O45
Molecular Weight:
3741.10
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light
Product Name
Beclin-1 Activator I, TAT-Beclin-1, Scrambled,
assay
≥95% (HPLC)
Quality Segment
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic), protect from light
color
white
solubility
water: 25 mg/mL
storage temp.
2-8°C
General description
Beclin-1 (267-284), a randomly shuffled peptideis made cell-permeable by attaching covalently to a human immunodeficiency virus(HIV)-1 Tat protein transduction domain via a diglycine linker. Beclin-1activating peptide I, TAT-Beclin-1, is observed to promote autophagy invitro and in vivo in pharmacological research.
Biochem/physiol Actions
Cell permeable: yes
Reversible: yes
Packaging
Packaged under inert gas
Other Notes
H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg~Gly-Gly~Val-Gly-Asn-Asp-Phe-Phe-Ile-Asn-His-Glu-Thr-Thr-Gly-Phe-Ala-Thr-Glu-Trp-OH
Liu, Y., et al. 2013. Proc. Natl. Acad. Sci. USA110, 20364.
Shoji-Kawata, S., et al. 2013. Nature.494, 201.
Shoji-Kawata, S., et al. 2013. Nature.494, 201.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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