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538903

Prostaglandin E₁

Name: Prostaglandin E<SUB>1</SUB>
Brand: MM

≥98% (HPLC), adenylate cyclase activity activator, solid

Synonym(s):

Prostaglandin E₁, PGE₁

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₃₄O₅

CAS Number:

745-65-3

Molecular Weight:

354.48

UNSPSC Code:

12352211

NACRES:

NA.77

MDL number:

MFCD00077860

eCl@ss:

42020658

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

OK to freeze

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Properties

Product Name

Prostaglandin E₁, Activates adenylate cyclase activity via a G-protein coupled receptor.

Quality Segment

100

description

Merck USA index - 14, 7876

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

white to off-white

solubility

ethanol: 50 mg/mL, methanol: 50 mg/mL, DMSO: soluble

shipped in

wet ice

storage temp.

−20°C

SMILES string

O[C@H]1[C@@H]([C@H](C(=O)C1)CCCCCCC(=O)O)\C=C\[C@@H](O)CCCCC

InChI

1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

InChI key

GMVPRGQOIOIIMI-DWKJAMRDSA-N

Description

General description

Activates adenylate cyclase activity via a G-protein coupled receptor.

Biochem/physiol Actions

Product does not compete with ATP.

Reversible: no

Cell permeable: no

Primary Target
Activates adenylate cyclase activity

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 1 month at -20°C.

Other Notes

Ammer, H. and Schulz, R. 1993. Mol. Pharmacol. 43, 556.
Rubin, D. and Laposata, M. 1991. J. Biol. Chem.266, 23618.
Kurstjens, N.P., et al. 1990. Biochem. Biophys. Res. Commun.167, 1162.
Krakauer, K.A., et al. 1986. Prostaglandins32, 301.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

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Pictograms

GHS06

Signal Word

Danger

Hazard Codes

H301

Precautionary Statements

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)