539522
PKCε Translocation Inhibitor Peptide
The PKCε Translocation Inhibitor Peptide, Negative Control controls the biological activity of PKCε. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Synonym(s):
PKCε Translocation Inhibitor Peptide, Protein Kinase Cε Translocation Inhibitor I, EAVSLKPT, PKCε Translocation Inhibitor I, PKCε-RACK2 Interaction Inhibitor I
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About This Item
Empirical Formula (Hill Notation):
C37H65N9O13
Molecular Weight:
843.96
NACRES:
NA.77
UNSPSC Code:
12352202
Assay:
≥97% (HPLC)
Form:
lyophilized solid
Storage condition:
OK to freeze, desiccated (hygroscopic)
Quality Segment
assay
≥97% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white
solubility
water: 3 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
An octapeptide that selectively inhibits the translocation of protein kinase Cε to subcellular sites in a reversible manner. Inhibition of PKCε translocation is known to specifically block phorbol ester- or norepinephrine-mediated regulation of contraction in cardiomyocytes.
Biochem/physiol Actions
Cell permeable: no
Primary Target
PKCε Translocation
PKCε Translocation
Product does not compete with ATP.
Reversible: yes
Physical form
Supplied as a trifluoroacetate salt.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 6 months at -20°C.
Other Notes
H-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
Yedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.
Johnson, J.A., et al. 1996. J. Biol. Chem.271, 24962.
Johnson, J.A., et al. 1996. J. Biol. Chem.271, 24962.
Legal Information
Sold under license of U.S. Patent 5,783,405.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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