Key Documents

COA/COQ

539560

PKC Inhibitor Peptide 19-36

Name: PKC Inhibitor Peptide 19-36
Brand: MM

The PKC Inhibitor Peptide 19-36 controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Synonym(s):

PKC Inhibitor Peptide 19-36, Protein Kinase C Inhibitor Peptide 19-36, RFARKGALRQKNVHEVKN

Sign Into View Organizational & Contract Pricing

Select a Size

All Photos(1)

About This Item

Empirical Formula (Hill Notation):

C₉₃H₁₅₉N₃₅O₂₄

Molecular Weight:

2151.48

UNSPSC Code:

12352200

Quality Level

100

Assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white to off-white

solubility

water: 0.1%

shipped in

ambient

storage temp.

−20°C

General description

Acts as pseudosubstrate by binding to the active sites of protein kinase C. A potent, reversible, and substrate competitive inhibitor of protein kinase C (K_i = 147 nM) but not of protein kinase A (IC₅₀ = 423 µM).

Biochem/physiol Actions

Cell permeable: no

Primary Target
PKC

Product does not compete with ATP.

Reversible: yes

Target K_i: 147 nM against protein kinase C

Packaging

Yes

Physical form

Supplied as a trifluoroacetate salt.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 weeks at -20°C.

Other Notes

H-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-His-Glu-Val-Lys-Asn-OH

Makowske, M. and Rosen, O.M. 1989. J. Biol. Chem.264, 16155.
House, C. and Kemp, B.E. 1987. Science238, 1726.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)