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Merck

573105

STAT3 Inhibitor Peptide, Cell-permeable, Inactive Control

The STAT3 Inhibitor Peptide, Cell-permeable, Inactive Control controls the biological activity of STAT3.

Synonym(s):

STAT3 Inhibitor Peptide, Cell-permeable, Inactive Control

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About This Item

Empirical Formula (Hill Notation):
C92H156N20O21
Molecular Weight:
1878.34
UNSPSC Code:
12352200

Product Name

STAT3 Inhibitor Peptide, Cell-permeable, Inactive Control, The STAT3 Inhibitor Peptide, Cell-permeable, Inactive Control controls the biological activity of STAT3.

assay

≥97% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)
protect from light

color

off-white

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Disclaimer

Toxicity: Standard Handling (A)

General description

A cell-permeable, non-phosphorylated inactive control peptide for STAT3 cellular function studies utilizing STAT3 Inhibitor PpYLKTK-mts (Cat. No. 573096).
The STAT3 Inhibitor Peptide, Cell-permeable, Inactive Control controls the biological activity of STAT3.

Other Notes

H-Pro-Tyr-Leu-Lys-Thr-Lys-Ala-Ala-Val-Leu-Leu-Pro-Val-Leu-Leu-Ala-Ala-Pro-OH
Turkson, J., et al. 2001. J. Biol. Chem.276, 45443.

Packaging

Packaged under inert gas

Physical form

Supplied as a trifluoroacetate salt.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

hcodes

H412

Hazard Classifications

Aquatic Chronic 3

Storage Class

11 - Combustible Solids

wgk

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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JAK/STAT Signaling Research Focus

The Janus kinase (JAK)/signal transducers and activators of transcription (STAT) signaling pathway plays an important role in cell proliferation, cell differentiation, cell migration, and cell death. It is the principal signaling mechanism for a variety of cytokines and growth factors. Constitutive activation or dysregulation of JAK/STAT signaling can result in inflammatory disease, erythrocytosis, gigantism, and leukemia.

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