581500
TEMPOL
≥95% (HPLC), crystals,powder, free radical scavenger and nitric oxide spin trap, Calbiochem®
Synonym(s):
TEMPOL, 4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C9H18NO2
CAS Number:
Molecular Weight:
172.24
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Form:
crystals, powder
Storage condition:
OK to freeze, protect from light
Product Name
TEMPOL, A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap.
Quality Segment
description
RTECS - TN8991000
assay
≥95% (HPLC)
form
crystals, powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
orange
solubility
DMSO: 5 mg/mL, ethanol: soluble, water: soluble
shipped in
ambient
storage temp.
−20°C
SMILES string
[N+]1(C(CC(CC1(C)C)O)(C)C)[O-]
InChI
1S/C9H18NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11H,5-6H2,1-4H3
InChI key
UZFMOKQJFYMBGY-UHFFFAOYSA-N
General description
A stable, cell-permeable nitroxide free radical that acts as a radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.
A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
Free radical scavenger and nitric oxide spin trap
Free radical scavenger and nitric oxide spin trap
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Preparation Note
Prepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).
Other Notes
Gariboldi, M.B., et al. 2000. Free Radic. Biol. Med.29, 633.
Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo)41, 103.
Mota-Filipe, H., et al. 1999. Shock 12, 255.
Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo)41, 103.
Mota-Filipe, H., et al. 1999. Shock 12, 255.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2 Oral
target_organs
Liver,spleen
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
294.8 °F - DIN 51758
flash_point_c
146 °C - DIN 51758
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.