612075
Thyroxine-Binding Globulin, Human
Liver glycoprotein and a major thyroid hormone carrier in serum. Exhibits high sequence similarity with α1-antitrypsin.
Synonym(s):
hTBG
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About This Item
NACRES:
NA.25
UNSPSC Code:
12352202
Form:
liquid
Assay:
≥95.0% (SDS-PAGE)
Quality Segment
assay
≥95.0% (SDS-PAGE)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
wet ice
storage temp.
−20°C
General description
M.W. 54,000-64,000.
Native, human thyroxine-binding globulin. Liver glycoprotein and a major thyroid hormone carrier in serum. Exhibits high sequence similarity with α1-antitrypsin. Its affinity for the hormone is thought to be temperature-sensitive.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In 140 mM NaCl, 10 mM Tris, 0.1% NaN₃, pH 8.0. Sterile-filtered.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
Miura, Y., et al. 1993. Endocrinol. J. 40, 127.
Janssen, O.E., et al. 1992. J. Biol. Chem.267, 13998.
Janssen, O.E., et al. 1992. J. Biol. Chem.267, 13998.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
12 - Non Combustible Liquids
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