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Merck

672112

Urokinase, Human Urine

Synonym(s):

Urokinase, Human Urine, uPA

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About This Item

CAS Number:
EC Number:
UNSPSC Code:
12352202
NACRES:
NA.25
MDL number:

description

Merck USA index - 14, 9887

form

lyophilized solid

specific activity

≥100,000 units/mg protein

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

shipped in

ambient

storage temp.

−20°C

Quality Level

Disclaimer

Toxicity: Standard Handling (A)

General description

Native urokinase from human urine. A thrombolytic agent that converts plasminogen to plasmin. A mixture of high molecular weight (54 kDa) and low molecular weight (33 kDa) urokinase.
Note: 1 unit = 1 CTA unit = 0.7 Ploug units. 1 KU = 1000 units.

Other Notes

Bell, W.R. 1975. Semin. Thromb. Res.2, 1.
Johnson, A.J., et al. 1969. Thromb. Diath. Haemorrh. 21, 259.
One unit is defined as the amount of enzyme equal to an international standard tested by the fibrinolytic method of Johnson, et al.

Physical form

Lyophilized from 200 mM mannitol, 100 mM NaCl, 50 mM Tris-HCl, 0.1% PEG, pH 7.5.

Preparation Note

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.
Prepared from urine of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitute in distilled H₂O

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3


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