VEGF₁₂₁, Human, Recombinant, S. frugiperda

Recombinant, human VEGF₁₂₁ (121-amino acid splice variant of the human vascular endothelial growth factor VEGF) expressed in S. frugiperda insect cells. VEGF₁₂₁ is dominantly expressed in most tumor cell lines. Forms a biological active homodimer and evidence suggests that it is also biologically active as a heterodimer with other VEGF splice variants or PIGF.

Recombinant, human VEGF₁₂₁ (121-amino acid splice variant of the human vascular endothelial growth factor VEGF) expressed in S. frugiperda insect cells. VEGF₁₂₁ is dominantly expressed in most tumor cell lines. Forms a biologically active homodimer and evidence suggests that it is also biologically active as a heterodimer with other VEGF splice variants or PIGF.

ED₅₀ ≥1 ng/ml as measured by the stimulation of ³H-thymidine incorporation by human umbilical vein endothelial cells and bovine aortic endothelial cells. In vivo effects using the 13-day-old chick chorioallantoic membrane (CAM) assay can be seen between 0.5-4 µg

Following reconstitution, aliquot and freeze at -70°C. Stock solutions are stable for up to 3 months at -70°C.

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Toxicity: Standard Handling (A)