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8.03649

N,N′-Diisopropylcarbodiimide

≥99.0% (GC), for peptide synthesis

Synonym(s):

N,N′-Diisopropylcarbodiimide

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About This Item

Linear Formula:
(CH3)2CHN=C=NCH(CH3)2
CAS Number:
693-13-0
Molecular Weight:
126.20
UNSPSC Code:
12352111
EC Index Number:
211-743-7
NACRES:
NA.22
MDL number:
MFCD00065689
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Product Name

N,N′-Diisopropylcarbodiimide, for synthesis

Quality Level

200

assay

≥99.0% (GC)

form

liquid

reaction suitability

reaction type: Coupling Reactions

bp

145-148 °C/1013 hPa

transition temp

flash point 33 °C

density

0.81 g/cm3 at 20 °C

application(s)

peptide synthesis

storage temp.

2-30°C

SMILES string

N(=C=NC(C)C)C(C)C

InChI

1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3

InChI key

BDNKZNFMNDZQMI-UHFFFAOYSA-N

General description

N,N′-Diisopropylcarbodiimide(DIC) is a liquid carbodiimide that contains the functional group RN=C=NR. It is soluble in most organic solvents. DIC is used as a coupling agent in peptide synthesis.

Application

  • Synthesis, structure and reactivity study of magnesium amidinato complexes derived from carbodiimides and N, N′-bis (2, 6-diisopropylphenyl)-1, 4-diaza …: This study involved the preparation of magnesium amidinato complexes using N,N′-Diisopropylcarbodiimide, exploring their structural and reactive properties in various chemical transformations (S Anga, J Bhattacharjee, A Harinath, TK Panda, 2015).

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.813 - 0.815
Identity (IR): passes test

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Eye Dam. 1 - Flam. Liq. 3 - Resp. Sens. 1 - Skin Sens. 1

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

91.4 °F

flash_point_c

33 °C

Certificates of Analysis (COA)

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A solvent-reagent selection guide for Steglich-type esterification of carboxylic acids
Jordan A, et al.
Green Chemistry, 23(17), 6405-6413 (2021)
Diisopropylcarbodiimide
Verma A
Synlett, 23(07), 1099-1100 (2012)