8.51011
MSNT
Novabiochem®
Synonym(s):
MSNT, 1-(Mesitylene-2-sulfonyl)-3-nitro-1H-1,2,4-triazole
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About This Item
Empirical Formula (Hill Notation):
C11H12N4O4S
CAS Number:
Molecular Weight:
296.30
UNSPSC Code:
12352005
MDL number:
product line
Novabiochem®
assay
≥95.0% (HPLC)
form
powder
reaction suitability
reaction type: Coupling Reactions
manufacturer/tradename
Novabiochem®
storage temp.
15-25°C
InChI
1S/C11H12N4O4S/c1-7-4-8(2)10(9(3)5-7)20(18,19)14-6-12-11(13-14)15(16)17/h4-6H,1-3H3
InChI key
SFYDWLYPIXHPML-UHFFFAOYSA-N
General description
This versatile reagent was originally used as a coupling reagent in phosphotriester oligonucleotide synthesis [1-3]. In recent years, it has been increasingly used for the esterification of Fmoc-amino acids onto solid phase synthesis supports [4-12]. It has proved particularly effective in difficult cases involving unreactive linkers [8, 9] or enantiomerization prone amino acids [7]. In an investigation [6] into ester formation, in which the alcohol or carboxylic acid component was immobilized on a solid support, MSNT was found to give the best results of all the reagents tested (DCC, DCC/HOBt, DCC/DMAP, Ph3P/DEAD).
The product number for this product was previously 01-62-0021.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
The product number for this product was previously 01-62-0021.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Analysis Note
Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Other Notes
Replaces: 01-62-0021
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Certificates of Analysis (COA)
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