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8.52014

Fmoc-Nle-OH

Name: Fmoc-Nle-OH
Brand: MM

≥98.0% (HPLC), for peptide synthesis, Novabiochem^®

Synonym(s):

Fmoc-Nle-OH, N-α-Fmoc-L-norleucine

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₂₃NO₄

CAS Number:

77284-32-3

Molecular Weight:

353.41

UNSPSC Code:

12352209

NACRES:

NA.22

MDL number:

MFCD00037537

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Properties

Product Name

Fmoc-Nle-OH, Novabiochem^®

Quality Level

200

product line

Novabiochem^®

assay

≥96.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem^®

mp

135-145 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-30°C

SMILES string

N(=C(/[O-])\OCC1c2c(cccc2)c3c1cccc3)/[C@H](CCCC)C(=O)O

InChI

1S/C21H23NO4/c1-2-3-12-19(20(23)24)22-21(25)26-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,2-3,12-13H2,1H3,(H,22,25)(H,23,24)/p-1/t19-/m1/s1

InChI key

VCFCFPNRQDANPN-LJQANCHMSA-M

Description

General description

Standard building block for introduction of norleucine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (25 mmole in 50 ml DMF): clearly soluble
UV/VIS (E(450 bis 600 nm)): ≤ 50 mAU
Assay (acidimetric): ≥ 96.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-1028

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c