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8.52030

Fmoc-Thr-OH

Novabiochem®

Synonym(s):

Fmoc-Thr-OH, N-α-Fmoc-L-threonine

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About This Item

Empirical Formula (Hill Notation):
C19H19NO5
CAS Number:
73731-37-0
Molecular Weight:
341.36
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:
MFCD00792901
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Quality Level

200

product line

Novabiochem®

assay

≥93.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

90-100 °C

application(s)

peptide synthesis

functional group

hydroxyl

storage temp.

2-30°C

SMILES string

N([C@@H]([C@@H](O)C)C(=O)[O-])C(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C19H19NO5/c1-11(21)17(18(22)23)20-19(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16-17,21H,10H2,1H3,(H,20,24)(H,22,23)/p-1/t11-,17-/m0/s1

InChI key

OYULCCKKLJPNPU-GTNSWQLSSA-M

General description

Useful derivative for the synthesis of phosphothreonine peptides by the Fmoc SPPS global phosphorylation methodology.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS


Literature references

[1] P. M. Fischer, et al. (1991) Int. J. Peptide Protein Res., 38, 491

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011C)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 93.0 %
Water (K. F.): ≤ 6.00 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1060

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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