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Merck

8.52222

Fmoc-Ala-OPfp

Novabiochem®

Synonym(s):

Fmoc-Ala-OPfp, N-α-Fmoc-L-alanine pentafluorophenyl ester

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About This Item

Empirical Formula (Hill Notation):
C24H16F5NO4
CAS Number:
Molecular Weight:
477.38
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:
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Quality Segment

product line

Novabiochem®

assay

≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

170-185 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

15-25°C

SMILES string

Fc1c(c(c(c(c1F)F)OC(=O)[C@@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)C)F)F

InChI

1S/C24H16F5NO4/c1-11(23(31)34-22-20(28)18(26)17(25)19(27)21(22)29)30-24(32)33-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,30,32)/t11-/m0/s1

InChI key

CJXZXBGKOSXBFR-NSHDSACASA-N

General description

Pre-formed pentafluorophenyl ester for coupling of alanine amino-acid residues by Fmoc SPPS. Use enables bromophenol blue monitoring of amide bond formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): -25.0 - -20.0 °
DCU (DC (0003)): ≤ 2 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1500

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


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Exclamation mark

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Warning

hcodes

Hazard Classifications

Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3



Certificates of Analysis (COA)

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