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Merck

8.52223

Fmoc-Ile-OPfp

Novabiochem®

Synonym(s):

Fmoc-Ile-OPfp, N-α-Fmoc-L-isoleucine pentafluorophenyl ester

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About This Item

Empirical Formula (Hill Notation):
C27H22F5NO4
CAS Number:
Molecular Weight:
519.46
UNSPSC Code:
12352209
MDL number:
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Quality Segment

product line

Novabiochem®

assay

≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

15-25°C

InChI

1S/C27H22F5NO4/c1-3-13(2)24(26(34)37-25-22(31)20(29)19(28)21(30)23(25)32)33-27(35)36-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18,24H,3,12H2,1-2H3,(H,33,35)/t13-,24-/m0/s1

InChI key

FYZSBHSHLNJGPS-RZFZLAGVSA-N

General description

Pre-formed pentafluorophenyl ester for coupling of isoleucine amino-acid residues by Fmoc SPPS. Use enables bromophenol blue monitoring of amide bond formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): -15.0 - -12.0 °
DCU (DC (0004)): ≤ 5 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1509

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


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Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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