8.52323
Fmoc-homopropargylglycine
Novabiochem®
Synonym(s):
Fmoc-homopropargylglycine
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About This Item
Empirical Formula (Hill Notation):
C21H19NO4
CAS Number:
Molecular Weight:
349.38
MDL number:
UNSPSC Code:
12352209
product line
Novabiochem®
form
solid
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
alkyne
storage temp.
15-25°C
SMILES string
N([C@@H](CCC#C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
InChI
1S/C21H19NO4/c1-2-3-12-19(20(23)24)22-21(25)26-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h1,4-11,18-19H,3,12-13H2,(H,22,25)(H,23,24)/t19-/m0/s1
InChI key
IISRBJULQYVYGV-IBGZPJMESA-N
General description
Building block for the introduction by Fmoc SPPS of an amino acid bearing an alkyne side chain. Such derivatives are useful tools for the synthesis of cyclic peptides by an alkyne-alkyne Glaser coupling, involving Cu(OAc)2/pyridine and heating to 60 °C using microwaves.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_c
Not applicable
Certificates of Analysis (COA)
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