8.52324
Fmoc-bishomopropargylglycine
Novabiochem®
Synonym(s):
Fmoc-bishomopropargylglycine
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About This Item
Empirical Formula (Hill Notation):
C22H21NO4
Molecular Weight:
363.41
NACRES:
NA.22
UNSPSC Code:
12352209
Product Name
Fmoc-bishomopropargylglycine, Novabiochem®
application(s)
peptide synthesis
product line
Novabiochem®
form
solid
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
functional group
alkyne
storage temp.
15-25°C
Quality Level
Analysis Note
Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
General description
Building block for the introduction by Fmoc SPPS of an amino acid bearing an alkyne side chain. Such derivatives are useful tools for the synthesis of cyclic peptides by an alkyne-alkyne Glaser coupling, involving Cu(OAc)2/pyridine and heating to 60 °C using microwaves.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Guide to Selection of Orthogonally -Protected Building Blocks for Fmoc SPPS
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Guide to Selection of Orthogonally -Protected Building Blocks for Fmoc SPPS
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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