Skip to Content
Merck

Key Documents

View All Documentation

8.52339

Fmoc-Pen(Trt)-OH

≥98.0% (HPLC), for peptide synthesis, Novabiochem®

Synonym(s):

Fmoc-Pen(Trt)-OH, Fmoc-α, α-dimethyl-Cys(Trt)-OH,Fmoc-S-trityl-L-penicillamine

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C39H35NO4S
CAS Number:
201531-88-6
Molecular Weight:
613.76
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:
MFCD00237388
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Fmoc-Pen(Trt)-OH, Novabiochem®

Quality Level

200

product line

Novabiochem®

assay

≥98% (TLC), ≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

thiol

storage temp.

15-25°C

SMILES string

S(C([C@H](NC(=O)OCC4c5c(cccc5)c6c4cccc6)C(=O)O)(C)C)C(c3ccccc3)(c2ccccc2)c1ccccc1

InChI

1S/C39H35NO4S/c1-38(2,45-39(27-16-6-3-7-17-27,28-18-8-4-9-19-28)29-20-10-5-11-21-29)35(36(41)42)40-37(43)44-26-34-32-24-14-12-22-30(32)31-23-13-15-25-33(31)34/h3-25,34-35H,26H2,1-2H3,(H,40,43)(H,41,42)/t35-/m1/s1

InChI key

XSGMGAINOILNJR-PGUFJCEWSA-N

General description

Fmoc-Pen(Trt)-OH is the standard building block for the introduction of penicillamine amino-acid residues by Fmoc SPPS. The side-chain thiol protecting group (Trt) is removed during the standard TFA-mediated cleavage reaction.

Associated Protocols and Technical Articles:
Cleavage and Deprotection Protocols for Fmoc SPPS

Application

Fmoc-Pen(Trt)-OH has been recently used in the synthesis of disulfide surrogate peptides.

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Still not finding the right product?

Explore all of our products under Fmoc-Pen(Trt)-OH

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library