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Merck

8.55085

HMPA-NovaGel

Novabiochem®

Synonym(s):

4-Hydroxymethylphenoxyacetyl NovaGel

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About This Item

NACRES:
NA.22
UNSPSC Code:
13111023
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Quality Level

product line

NovaGel, Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

alcohol

storage temp.

2-8°C

General description

This resin is prepared by derivatization of aminomethyl NovaGel with the TFA-labile 4-hydroxymethylphenoxyacetic acid linker. NovaGel resins combine the high functionality of polystyrene resins with the excellent swelling properties of PEG-PS type supports [1].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

[1] J. H. Adams, et al. (1998) J. Org. Chem., 63, 3706.

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.50 - 0.80 mmol/g
Swelling Volume (in DMF): lot specific result

Other Notes

Replaces: 01-64-0284

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.