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ABC257

Anti-EPHB4 Antibody

Name: Anti-EPHB4 Antibody
Brand: MM

from rabbit, purified by affinity chromatography

Synonym(s):

Ephrin type-B receptor 4, Hepatoma transmembrane kinase, Tyrosine-protein kinase TYRO11

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

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Properties

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

species reactivity (predicted by homology)

mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), rat (based on 100% sequence homology)

technique(s)

western blot: suitable

NCBI accession no.

NP_004435

UniProt accession no.

P54760

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... EPHB4(2050)

Description

General description

Ephrin type-B receptor 4 (EPHB4) is also called Hepatoma transmembrane kinase, and Tyrosine-protein kinase TYRO11. EPHB4 is a receptor tyrosine kinase that together with EFNB2 is critical to heart morphogenesis and angiogenesis through the regulation of cell adhesion and cell migration. EPHB4 is expressed in placenta, kidney, liver, lung, pancreas, skeletal muscle, and heart, as well as primitive and myeloid hematopoietic cells.

~120 kDa observed. The calculated molecular weight is 108 kDa, however EPHB4 has been shown as a ~120 kDa band in western blots (Lee, Y. C., et al. (2005). BMC Cancer. 5(119):1-11).

Immunogen

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human EPHB4.

Application

Detect EphB4 using this rabbit polyclonal antibody, Anti-EPHB4 Antibody validated for use in western blotting.

Analysis Note

Evaluated by Western Blotting in PC3 tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected EPHB4 in 10 µg of PC3 tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c