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Merck

AB3704

Anti-Orexin-A Antibody

serum, Chemicon®

Synonym(s):

Anti-NRCLP1, Anti-OX, Anti-PPOX

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-Orexin-A Antibody, serum, Chemicon®

biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... PPOX(5498)

Application

Detect Orexin-A using this Anti-Orexin-A Antibody validated for use in IH.
Immunohistochemistry: 1:1,000-1:2,000. The antibody shows intense labeling of Orexin-A neurons with low background.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
CNS Control of Metabolism

Circadian Rhythm & Sleep

Biochem/physiol Actions

Orexin-A.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Synthetic peptide corresponding to the C-terminal portion of the bovine Orexin-A peptide.

Physical form

Rabbit serum. Lyophilized. Reconstitute with 50 mL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.

Preparation Note

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hannah Bruguier et al.
The Journal of comparative neurology, 528(17), 2956-2977 (2020-04-09)
The human claustrum, a major hub of widespread neocortical connections, is a thin, bilateral sheet of gray matter located between the insular cortex and the striatum. The subplate is a largely transient cortical structure that contains some of the earliest
Audrey Chen et al.
eNeuro, 4(1) (2017-03-10)
Pharmacological studies in mammals and zebrafish suggest that histamine plays an important role in promoting arousal. However, genetic studies using rodents with disrupted histamine synthesis or signaling have revealed only subtle or no sleep/wake phenotypes. Studies of histamine function in
Tanya Calvey et al.
Journal of chemical neuroanatomy, 70, 42-57 (2015-11-13)
The nuclear organization of the cholinergic, catecholaminergic, serotonergic and orexinergic systems in the brains of three species of strepsirrhine primates is presented. We aimed to investigate the nuclear complement of these neural systems in comparison to those of simian primates
Sukanya Biswabharati et al.
eNeuro, 5(5) (2018-11-13)
The role of orexin during development, and especially in terms of spinal cord function, is not well understood. It is for this reason that we focused on the network actions of orexin during the first week of development. We found
Daniel S Wheeler et al.
The European journal of neuroscience, 40(2), 2359-2377 (2014-04-23)
Orexin (hypocretin) and melanin-concentrating hormone (MCH) neurons are unique to the lateral hypothalamic (LH) region, but project throughout the brain. These cell groups have been implicated in a variety of functions, including reward learning, responses to stimulants, and the modulation

Global Trade Item Number

SKUGTIN
AB370404053252589218

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