CBL468
Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6
clone HC1/6, Chemicon®, from mouse
Synonym(s):
CD31
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
HC1/6, monoclonal
Application:
FACS, IHC (p), IP
Citations:
15
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
clone
HC1/6, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... PECAM1(5175)
Immunogen
Epitope: domains 3-6 of human PECAM-1
Application
Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6 is an antibody against PECAM-1 for use in FC, IH, IH(P) & IP.
Studies of the role of CD31 in leucocyte migration into inflammatory sites and in the process of angiogenesis
This antibody will stain frozen tissue sections
Suitable for immunoprecipitation studies
Suitable for flow cytometry either indirectly or directly when labelled with FITC or R-PE
Suitable for use on formalin fixed paraffin embedded sections after protease pre-treatment.
Optimal working dilutions must be determined by the end user.
This antibody will stain frozen tissue sections
Suitable for immunoprecipitation studies
Suitable for flow cytometry either indirectly or directly when labelled with FITC or R-PE
Suitable for use on formalin fixed paraffin embedded sections after protease pre-treatment.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Reacts with a 130-140 kDa transmembranous glycoprotein that is expressed widely amongst cells of the vascular compartment. CD31 is expressed on platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney as well as in skin biopsies from conditions such as sarcoidosis and lepromatous leprosy.
FUSION PARTNER: P3-x63Ag8.653 myeloma cell line
FUSION PARTNER: P3-x63Ag8.653 myeloma cell line
Physical form
Format: Purified
Analysis Note
Control
Activated microglial cells
Activated microglial cells
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Related Content
Fumiko Obata et al.
Toxins, 14(2) (2022-02-25)
Shiga toxin-producing Escherichia coli (STEC) causes proximal tubular defects in the kidney. However, factors altered by Shiga toxin (Stx) within the proximal tubules are yet to be shown. We determined Stx receptor Gb3 in murine and human kidneys and confirmed
Yu-Ting Huang et al.
Cellular signalling, 20(8), 1521-1527 (2008-05-27)
Sphingosine 1-phosphate (S1P) is a multifunctional phospholipid which acts through a specific family of G protein-coupled receptors. Platelet/endothelial cell adhesion molecule-1 (PECAM-1) form trans-homophilic binding at lateral cell border. Upon stimulation, its cytoplasmic tyrosine residues could be phosphorylated and interact
Guiting Lin et al.
Stem cells and development, 17(6), 1053-1063 (2008-07-04)
Adipose tissue-derived stem cells (ADSC) are routinely isolated from the stromal vascular fraction (SVF) of homogenized adipose tissue. Freshly isolated ADSC display surface markers that differ from those of cultured ADSC, but both cell preparations are capable of multipotential differentiation.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| CBL468 | 04053252331015 |