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HCABMAG-13K

MILLIPLEX® Human Cancer Autoantibody Panel 15-Plex

Configurable Human Cancer Autoantibody IgG 15-Plex Panel

Synonym(s):

IgG cancer autoantibody profiling, Luminex® cancer serology assay, oncology serology multiplex kit

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About This Item

NACRES:
NA.41
UNSPSC Code:
12161503

Product Name

MILLIPLEX® Human Cancer Autoantibody Panel 15-Plex,

description

Configurable Human Cancer Autoantibody IgG 15-Plex Panel

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

serum plasma

assay range

inter-assay cv: <20%
intra-assay cv: <10%

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Cancer autoantibodies have been studied as reporters of early carcinogenesis and indicators of cancer prognosis. Autoantibodies to tumor-associated antigens are putative cancer biomarkers, as these autoantibodies are abundant, detectable in early stages, and stable in serum. These autoantibodies may be developed from humoral immune responses to the changes in the expression levels of tumor-associated self-antigens, misfolded proteins, mutant antigens, and proteins involved in inflammation and the cellular death process. While the frequency of cancer autoantibody responses to an individual tumor antigen is typically low, the response to a multiplexed panel of antigens could be much higher. An optimized multiplex autoantibody panel to common tumor-associated antigens can improve the potential of using autoantibodies as biomarkers to study cancer development and progression, and it can serve as a simple and affordable tool in evaluating large numbers of patient samples for multiple cancer types.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 15 analytes in human serum and plasma samples.

Analytes included: CCNB1/Cyclin B1, CTAG1B/NY-ESO-1, ENO1, Galectin-1 (GAL1), Galectin-3, ErbB2/HER2, HIF-1α, HSP60, IGF2BP2/IMP2, IGF2BP3/IMP3, Mucin-1 (MUC1), P16-INK4a, p53, Sox2, Survivin/BIRC5

Note: This is a qualitative assay.Assay Characteristics: Refer to kit protocol for assay cross-reactivity and precision.

Features and Benefits

  • Cancer Autoantibody Profiling: Simultaneously measure autoantibodies to 15 tumor-associated antigens, including p53, HER2/ErbB2, MUC1, NY-ESO-1, and Survivin. Built-In Quality Assurance: Includes 4 assay control beads for reproducibility.
  • Research Versatility: Ideal for studying tumor microenvironment dynamics, immune system engagement in cancer, and biomarker discovery for therapeutic monitoring.
  • Cost and Time Efficiency: Replace 15 individual assays with one multiplex panel, reducing costs, labor, and sample volume.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

wgk

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Please refer to KIT Component information

pdsc

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prtr

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fsl

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ishl_indicated

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ishl_notified

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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