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Merck

HCYTA-60K

MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Panel A

Configurable Human Cytokine/Chemokine/Growth Factor 48-Plex Panel A

Synonym(s):

Human cytokine multiplex kit, Luminex® human cytokine immunoassay, Millipore human cytokine panel

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84

Quality Level

200

species reactivity

human

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

cell culture supernatant(s)
plasma
serum

detection method

fluorometric (Luminex® xMAP®)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

General description

Cytokines, chemokines, and growth factors are key mediatorsof immune system functions capable of signaling through autocrine, paracrine,and endocrine mechanisms. Their pleiotropic immunomodulatory propertiesallow these biomolecules to react to diverse stimuli and regulate the immuneresponse, either promoting or inhibiting inflammation.

Application

  • MILLIPLEX® Qualified assays undergo rigorousassay development, verification, and Quality Control testing to achieve optimalperformance.
  • Simultaneously analyze up to 48 cytokine,chemokine, and growth factor biomarkers with bead-based multiplex assays usingLuminex technology, in human serum, plasma and cell culture samples.
  • Available analytes: sCD40L, EGF, Eotaxin, FGF-2,FLT-3L, Fractalkine, G-CSF, GM-CSF, GROα, IFNα2, IFNγ, IL-1α, IL-1β, IL-1RA,IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12 (p40), IL-12(p70), IL-13, IL-15, IL-17A, IL-17E/IL-25, IL-17F, IL-18, IL-22, IL-27, IP-10,MCP-1, MCP-3, M-CSF, MDC, MIG, MIP-1α, MIP-1β, PDGF-AA, PDGF-AB/BB, RANTES,TGFα, TNFα, TNFβ, VEGF-A

Features and Benefits

  • This panel is fully configurable, with options for custom bead premixing, fixed premixed and bulk premixed panels.
  • Save time and resources by simultaneously analyzing up to 48 analytes of your choice in a single sample
  • Requires a small sample volume (25 µL/well)
  • Choose same day or overnight incubation
  • Reliable and accurate performance with proven lot-to-lot consistency
  • Ready-to-use reagents
  • Comes with everything you need to run your assay
  • Includes a Serum Matrix to mimic the native sample environment in serum and plasma samples
  • Includes high and low Quality Controls

Packaging

96-well plate

Preparation Note

Recommended storage for kit components is 2 - 8°C.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

Unless otherwise stated in our catalogor other company documentation accompanying the product(s), our products areintended for research use only and are not to be used for any other purpose,which includes but is not limited to, unauthorized commercial uses, in vitrodiagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumptionor application to humans or animals.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

Target Organs

Respiratory Tract

Storage Class Code

10 - Combustible liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Liam J O'Neil et al.
Frontiers in immunology, 13, 958145-958145 (2022-09-27)
The development of autoantibody directed towards citrullinated proteins (ACPA) are predictive of RA in at-risk individuals. The biological events that underpin loss of immune tolerance and progression into inflammatory arthritis are not known. We sought to identify serum proteomic alterations
Qi Wang et al.
Frontiers in immunology, 13, 995223-995223 (2022-09-27)
In primary biliary cholangitis (PBC), the levels of serum IL-2 were involved in liver inflammation and immune changes. This study aimed to investigate the prognostic significance of serum IL-2 combined with total bilirubin (TBIL) in liver failure and cytokine changes
Teslin S Sandstrom et al.
Journal of virology, 95(9) (2021-02-12)
The use of unique cell surface markers to target and eradicate HIV-infected cells has been a longstanding objective of HIV-1 cure research. This approach, however, overlooks the possibility that intracellular changes present within HIV-infected cells may serve as valuable therapeutic
Kelsey E Huntington et al.
eLife, 10 (2021-01-15)
Although the range of immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is variable, cytokine storm is observed in a subset of symptomatic individuals. To further understand the disease pathogenesis and, consequently, to develop an additional tool for
Myung-Ho Kim et al.
The Journal of infectious diseases (2021-05-27)
We analyzed the plasma levels of interferons and cytokines, and the expression of interferon-stimulated genes in peripheral blood mononuclear cells in COVID-19 patients with different disease severity. Mild patients exhibited transient type I interferon responses, while ICU patients had prolonged
View All Related Papers

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Next-Generation Cytokine Multiplex Assays | MILLIPLEX® Assays

Cytokine multiplex assays allow researchers to easily investigate the immune system. The MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Multiplex Panels A and B are multiplex assays for cytokine detection that each offer a unique combination of 48 analytes that can be simultaneously analyzed in a small sample volume.

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Global Trade Item Number

SKUGTIN
HCYTA-60K-2504061841059455
HCYTA-60K-15C04061841059837
HCYTA-60K-45C04061841060130
HCYTA-60K-1204061841059325
HCYTA-60K-08C04061841059769
HCYTA-60K-3204061841059523
HCYTA-60K-18C04061841059868
HCYTA-60K-09C04061841059776
HCYTA-60K-1304061841059332
HCYTA-60K-0704061841059271
HCYTA-60K-1804061841059387
HCYTA-60K-1704061841059370
HCYTA-60K-2804061841059486
HCYTA-60K-38C04061841060062
HCYTA-60K-0904061841059295
HCYTA-60K-3304061841059530
HCYTA-60K-2604061841059462
HCYTA-60K-3804061841059585
HCYTA-60K-1904061841059394
HCYTA-60K-39C04061841060079
HCYTA-60K-3604061841059561
HCYTA-60K-4804061841059684
HCYTA-60K-4704061841059677
HCYTA-60K-30C04061841059981

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