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Merck

HCYTB-60K

Millipore

MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Panel B

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.77

usage

 kit sufficient for 96 wells

Quality Level

species reactivity

human

manufacturer/tradename

Milliplex®

parameter

25 μL sample volume (per well)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex® xMAP®)

shipped in

wet ice

storage temp.

2-8°C

General description

  • “Cytokine” is a general term used for a diverse group of small proteins, peptides or glycoproteins secreted by lymphocytes, monocytes, macrophages and other cells that regulate immune responses, hematopoiesis and lymphocyte development. Cytokines include interleukins, interferons, chemokines and other signaling molecules. Growth factors are extracellular polypeptides that have a positive effect on cell growth and proliferation. They can stimulate growth in a variety of different cell types. Growth factors and cytokines are similar in structure and the way of action. Individual cytokines or growth factors are produced by multiple cell types. This is different from hormones, which tend to be made by specialized glands. Each cytokine or growth factor acts through its own receptor on target cells to generate signaling pathways, and as a consequence to regulate biological processes. Some intracellular signaling components are shared between cytokines and growth factors. Expression of cytokines or growth factors and their receptors is highly regulated. De-regulation may contribute to many diseases such as infectious disease, autoimmune and chronic inflammatory disease, cardiovascular disease, metabolic syndrome, neurological disorders, and cancer. Cytokine and growth factor research plays a significant role in achieving a deeper understanding of the immune system and combating related diseases.The MILLIPLEX® portfolio offers the broadest selection of analytes across a wide range of disease states and species. Once the analytes of interest have been identified, you can rely on the quality that we build into each kit to produce results you can trust. In addition to the assay characteristics listed in the protocol, other performance criteria evaluated during the verification process include: cross-reactivity, dilution linearity, kit stability, and sample behavior (for example, detectability and stability).In addition, each panel and kit meet stringent manufacturing criteria to ensure batch to-batch reproducibility.

    The MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Panel B Magnetic Bead Panel enables you to focus on the therapeutic potential of cytokines and the modulation of cytokine expression. Coupled with the Luminex® xMAP® platform in a magnetic bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of dozens of analytes simultaneously, which can dramatically improve productivity.

    Research Category: Inflammation & Immunology

    Research sub-category:

    Inflammation & Autoimmune Mechanisms
  • Inflammation

Application

The MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Panel B Magnetic Bead Panel is a 48-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum or plasma samples and tissue/cell lysate and culture supernatant samples: 6Ckine, sCD137, sFAS, sFASL, APRIL, BAFF, BCA-1, CCL28, CTACK, CXCL16, ENA-78, Eotaxin-2, Eotaxin-3, GCP-2, Granzyme A, Granzyme B, HMGB1, I-309, IFNβ, IFNω, IL-11, IL-16, IL-20, IL-21, IL-23, IL-24, IL-28A, IL-29, IL-31, IL-33, IL-34, IL-35, I-TAC, LIF, Lymphotactin, MCP-2, MCP-4, MIP-1δ, MIP-3α, MIP-3β, MPIF-1, Perforin, SCF, SDF-1, TARC, TPO, TRAIL, TSLP.

Biochem/physiol Actions

There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

Target Organs

Respiratory Tract

Storage Class Code

10 - Combustible liquids


Certificates of Analysis (COA)

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Related Content

Cytokine multiplex assays allow researchers to easily investigate the immune system. The MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Multiplex Panels A and B are multiplex assays for cytokine detection that each offer a unique combination of 48 analytes that can be simultaneously analyzed in a small sample volume.

MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Panels A and B offer customizable options for analyzing nearly 100 cytokines.

Simplify protein biomarker discovery with the MILLIPLEX® PLEXpedition 115-Plex Multiplex Screening Panel. Effortlessly screen cytokines and other markers with Luminex® technology.

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Global Trade Item Number

SKUGTIN
HCYTB-60K-0204065268025857
HCYTB-60K-2204065268026052
HCYTB-60K-4204065268026250
HCYTB-60K-09C04065268026403
HCYTB-60K-0104065268025840
HCYTB-60K-19C04065268026502
HCYTB-60K-4004065268026236
HCYTB-60K-2104065268026045
HCYTB-60K-11C04065268026427
HCYTB-60K-3104065268026144
HCYTB-60K-0904065268025925
HCYTB-60K-12C04065268026434
HCYTB-60K-31C04065268026625
HCYTB-60K-22C04065268026533
HCYTB-60K-41C04065269370574
HCYTB-60K-32C04065269370536
HCYTB-60K-0404065268025871
HCYTB-60K-1404065268025970
HCYTB-60K-3404065268026175
HCYTB-60K-40C04065268026717
HCYTB-60K-0304065268025864
HCYTB-60K-4404065268026274
HCYTB-60K-23C04065268026540
HCYTB-60K-33C04065268026649

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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